Fragile X Mental Retardation Protein
"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
| Descriptor ID |
D051860
|
| MeSH Number(s) |
D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".
Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".
This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.
-
Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer. Crit Rev Biochem Mol Biol. 2020 10; 55(5):409-424.
-
FMR1 mRNA from full mutation alleles is associated with ABC-CFX scores in males with fragile X syndrome. Sci Rep. 2020 07 16; 10(1):11701.
-
Muscarinic M1 Receptor Modulation of Synaptic Plasticity in Nucleus Accumbens of Wild-Type and Fragile X Mice. ACS Chem Neurosci. 2018 09 19; 9(9):2233-2240.
-
Donepezil Reverses Dendritic Spine Morphology Adaptations and Fmr1 Epigenetic Modifications in Hippocampus of Adult Rats After Adolescent Alcohol Exposure. Alcohol Clin Exp Res. 2018 Apr; 42(4):706-717.
-
FMRP Mediates Chronic Ethanol-Induced Changes in NMDA, Kv4.2, and KChIP3 Expression in the Hippocampus. Alcohol Clin Exp Res. 2016 06; 40(6):1251-61.
-
Increased long-term potentiation at medial-perforant path-dentate granule cell synapses induced by selective inhibition of histone deacetylase 3 requires Fragile X mental retardation protein. Neurobiol Learn Mem. 2014 Oct; 114:193-7.
-
Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration. Neuron. 2014 May 07; 82(3):645-58.
-
Striking a balance in fragile X. Nat Med. 2013 Nov; 19(11):1370-1.
-
Glycogen synthase kinase-3 inhibitors reverse deficits in long-term potentiation and cognition in fragile X mice. Biol Psychiatry. 2014 Feb 01; 75(3):198-206.
-
Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity. Mol Cell Neurosci. 2013 Sep; 56:39-49.