"Poly(A)-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that bind to the 3' polyadenylated region of MRNA. When complexed with RNA the proteins serve an array of functions such as stabilizing the 3' end of RNA, promoting poly(A) synthesis and stimulating mRNA translation.
| Descriptor ID |
D039102
|
| MeSH Number(s) |
D12.776.157.725.452 D12.776.664.962.452
|
| Concept/Terms |
Poly(A)-Binding Proteins- Poly(A)-Binding Proteins
- Poly(A)-Binding Protein
- Poly A-Binding Proteins
- Poly A Binding Proteins
- Poly(A)+ mRNA Binding Protein
- Poly A-Binding Protein
- Poly A Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Poly(A)-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Poly(A)-Binding Proteins".
This graph shows the total number of publications written about "Poly(A)-Binding Proteins" by people in this website by year, and whether "Poly(A)-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Poly(A)-Binding Proteins" by people in Profiles.
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Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae. J Cell Biol. 2010 May 31; 189(5):813-27.
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Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal. J Biol Chem. 2004 Jun 04; 279(23):23988-95.
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Direct-rapid (DR) mutagenesis of large plasmids using PCR. Biotechniques. 1995 Oct; 19(4):559-64.
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Human immunodeficiency virus type 1 Rev is required in vivo for binding of poly(A)-binding protein to Rev-dependent RNAs. J Virol. 1994 Sep; 68(9):5433-8.