"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 2 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 2 | 4 |
| 2004 | 3 | 2 | 5 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 4 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 4 | 0 | 4 |
| 2011 | 2 | 3 | 5 |
| 2012 | 2 | 2 | 4 |
| 2013 | 4 | 3 | 7 |
| 2014 | 1 | 3 | 4 |
| 2016 | 2 | 0 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 4 | 5 |
| 2019 | 4 | 0 | 4 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
-
BAY 11-7082 inhibits the secretion of interleukin-6 by senescent human microglia. Biochem Biophys Res Commun. 2022 08 20; 617(Pt 1):30-35.
-
Kynurenine induces an age-related phenotype in bone marrow stromal cells. Mech Ageing Dev. 2021 04; 195:111464.
-
Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death Dis. 2021 01 04; 12(1):27.
-
MicroRNAs are critical regulators of senescence and aging in mesenchymal stem cells. Bone. 2021 01; 142:115679.
-
An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction. Life Sci. 2020 Oct 15; 259:118199.
-
Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle. ACS Nano. 2020 03 24; 14(3):2827-2846.
-
Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway. Exp Gerontol. 2020 02; 130:110805.
-
Sugar partitioning and source-sink interaction are key determinants of leaf senescence in maize. Plant Cell Environ. 2019 09; 42(9):2597-2611.
-
Oxidative stress induces senescence in breast cancer stem cells. Biochem Biophys Res Commun. 2019 07 05; 514(4):1204-1209.
-
Physician-Training Stress and Accelerated Cellular Aging. Biol Psychiatry. 2019 11 01; 86(9):725-730.