"Cycloheximide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
| Descriptor ID |
D003513
|
| MeSH Number(s) |
D03.383.621.808.240
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cycloheximide".
Below are MeSH descriptors whose meaning is more specific than "Cycloheximide".
This graph shows the total number of publications written about "Cycloheximide" by people in this website by year, and whether "Cycloheximide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 5 | 5 |
| 1996 | 0 | 2 | 2 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cycloheximide" by people in Profiles.
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Differential accumulation of secreted AbetaPP metabolites in ocular fluids. J Alzheimers Dis. 2010; 20(4):1243-53.
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Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome. DNA Repair (Amst). 2005 Dec 08; 4(12):1381-9.
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The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J Biol Chem. 2003 Nov 14; 278(46):45358-67.
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Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation. Neoplasia. 2002 May-Jun; 4(3):218-27.
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Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line. J Biol Chem. 2001 Aug 31; 276(35):32506-14.
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Cell death in spinal cord injury (SCI) requires de novo protein synthesis. Calpain inhibitor E-64-d provides neuroprotection in SCI lesion and penumbra. Ann N Y Acad Sci. 2001 Jun; 939:436-49.
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Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization. Shock. 2001 Apr; 15(4):291-6.
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Vaccinia virus blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activation. J Virol. 2001 Apr; 75(7):3185-96.
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Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid. Shock. 2000 Aug; 14(2):128-33.
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Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region. Biochemistry. 1999 Feb 16; 38(7):2189-99.