Activin Receptors, Type I
"Activin Receptors, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are several type I activin receptors. The major active ones are ALK-2 (ActR-IA) and ALK-4 (ActR-IB).
Descriptor ID |
D030201
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MeSH Number(s) |
D08.811.913.696.620.682.700.062.500 D12.776.543.750.750.400.820.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Activin Receptors, Type I".
Below are MeSH descriptors whose meaning is more specific than "Activin Receptors, Type I".
This graph shows the total number of publications written about "Activin Receptors, Type I" by people in this website by year, and whether "Activin Receptors, Type I" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2005 | 2 | 2 | 4 |
2006 | 1 | 1 | 2 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Activin Receptors, Type I" by people in Profiles.
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Identifying Chronic Obstructive Pulmonary Disease Genes: Shining the Light on Dark DNA. Am J Respir Cell Mol Biol. 2019 Apr; 60(4):373-374.
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Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects. BMC Dev Biol. 2006 Nov 01; 6:51.
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Left-right lineage analysis of the embryonic Xenopus heart reveals a novel framework linking congenital cardiac defects and laterality disease. Development. 2006 Apr; 133(7):1399-410.
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Left-right lineage analysis of AV cushion tissue in normal and laterality defective Xenopus hearts. Anat Rec A Discov Mol Cell Evol Biol. 2005 Dec; 287(2):1176-82.
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Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc Natl Acad Sci U S A. 2005 Nov 01; 102(44):15791-6.
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Developmental analysis of activin-like kinase receptor-4 (ALK4) expression in Xenopus laevis. Dev Dyn. 2005 Feb; 232(2):393-8.
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A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat Genet. 2005 Mar; 37(3):275-81.
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An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma. Arthritis Rheum. 2004 May; 50(5):1566-77.
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ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus. Dev Biol. 2004 Apr 15; 268(2):280-94.
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Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor. Circulation. 2002 Apr 09; 105(14):1672-8.