"Genes, fms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of genes originally isolated from the Susan McDonough strain of feline sarcoma virus (SARCOMA VIRUSES, FELINE). The proto-oncogene fms (c-fms) codes for the MCSF receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR). The oncogene fms (v-fms) codes for ONCOGENE PROTEIN GP140(V-FMS) which is a mutated form of the MCSF. The human c-fms gene is located between 5q33.2 and 5q33.3.
| Descriptor ID |
D016236
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.325
|
| Concept/Terms |
c-fms Genes- c-fms Genes
- Gene, c-fms
- Genes, c-fms
- c fms Genes
- c-fms Gene
- c-fms Proto-Oncogenes
- Proto-Oncogene, c-fms
- Proto-Oncogenes, c-fms
- c fms Proto Oncogenes
- c-fms Proto-Oncogene
v-fms Genes- v-fms Genes
- Gene, v-fms
- Genes, v-fms
- v fms Genes
- v-fms Gene
- v-fms Oncogenes
- Oncogene, v-fms
- Oncogenes, v-fms
- v fms Oncogenes
- v-fms Oncogene
|
Below are MeSH descriptors whose meaning is more general than "Genes, fms".
Below are MeSH descriptors whose meaning is more specific than "Genes, fms".
This graph shows the total number of publications written about "Genes, fms" by people in this website by year, and whether "Genes, fms" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genes, fms" by people in Profiles.
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Transcriptional control of the expression of the c-fms gene encoding the receptor for macrophage colony-stimulating factor (CSF-1). Immunobiology. 1996 Oct; 195(4-5):461-76.
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Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling. Mol Cell Biol. 1995 Feb; 15(2):693-703.
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Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J Exp Med. 1994 Dec 01; 180(6):2309-19.
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An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites. Mol Endocrinol. 1992 Jul; 6(7):1051-60.
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The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. Genes Dev. 1991 Oct; 5(10):1777-85.