"Genes, jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (jun) originally isolated from the avian sarcoma virus 17 (ASV 17). The proto-oncogene jun (c-jun) codes for a nuclear protein which is involved in growth-related transcriptional control. Insertion of c-jun into ASV-17 or the constitutive expression of the c-jun protein produces tumorgenicity. The human c-jun gene is located at 1p31-32 on the short arm of chromosome 1.
| Descriptor ID |
D016758
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.365
|
| Concept/Terms |
jun Proto-Oncogene- jun Proto-Oncogene
- Proto-Oncogene, jun
- Proto-Oncogenes, jun
- jun Proto Oncogene
- jun Proto-Oncogenes
jun Oncogene- jun Oncogene
- Oncogene, jun
- Oncogenes, jun
- jun Oncogenes
|
Below are MeSH descriptors whose meaning is more general than "Genes, jun".
Below are MeSH descriptors whose meaning is more specific than "Genes, jun".
This graph shows the total number of publications written about "Genes, jun" by people in this website by year, and whether "Genes, jun" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, jun" by people in Profiles.
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The ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene. Curr Alzheimer Res. 2015; 12(9):847-59.
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Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists. Br J Cancer. 2000 Oct; 83(7):906-13.
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Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase. Blood. 1998 Oct 01; 92(7):2450-60.
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Tyrosine phosphorylation of phosphatidylinositol 3-kinase and of the thromboxane A2 (TXA2) receptor by the TXA2 mimetic I-BOP in A7r5 cells. Biochem Pharmacol. 1997 Jun 15; 53(12):1823-32.
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Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. Mol Endocrinol. 1996 Sep; 10(9):1084-94.
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Ceramide activates the stress-activated protein kinases. J Biol Chem. 1995 Sep 29; 270(39):22689-92.
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Regulation of c-jun by lung carcinogens in Clara cells of hamsters. Carcinogenesis. 1994 Dec; 15(12):2789-93.
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Effect of combined treatment with interleukin-3 and interleukin-6 on 4-hydroperoxycyclo-phosphamide-induced programmed cell death or apoptosis in human myeloid leukemia cells. Exp Hematol. 1993 Dec; 21(13):1640-7.
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High-dose mitoxantrone induces programmed cell death or apoptosis in human myeloid leukemia cells. Blood. 1993 Nov 15; 82(10):3133-40.
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Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells. Leukemia. 1993 Apr; 7(4):563-8.