"Genes, myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
| Descriptor ID |
D016259
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.420
|
| Concept/Terms |
c-myc Genes- c-myc Genes
- Gene, c-myc
- Genes, c-myc
- c myc Genes
- c-myc Gene
c-myc Proto-Oncogenes- c-myc Proto-Oncogenes
- Proto-Oncogene, c-myc
- Proto-Oncogenes, c-myc
- c myc Proto Oncogenes
- c-myc Proto-Oncogene
v-myc Genes- v-myc Genes
- Gene, v-myc
- Genes, v-myc
- v myc Genes
- v-myc Gene
L-myc Proto-Oncogenes- L-myc Proto-Oncogenes
- L myc Proto Oncogenes
- L-myc Proto-Oncogene
- Proto-Oncogene, L-myc
- Proto-Oncogenes, L-myc
myc Oncogene- myc Oncogene
- Oncogene, myc
- Oncogenes, myc
- myc Oncogenes
N-myc Genes- N-myc Genes
- Gene, N-myc
- Genes, N-myc
- N myc Genes
- N-myc Gene
N-myc Proto-Oncogenes- N-myc Proto-Oncogenes
- N myc Proto Oncogenes
- N-myc Proto-Oncogene
- Proto-Oncogene, N-myc
- Proto-Oncogenes, N-myc
v-myc Oncogenes- v-myc Oncogenes
- Oncogene, v-myc
- Oncogenes, v-myc
- v myc Oncogenes
- v-myc Oncogene
L-myc Genes- L-myc Genes
- Gene, L-myc
- Genes, L-myc
- L myc Genes
- L-myc Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myc".
Below are MeSH descriptors whose meaning is more specific than "Genes, myc".
This graph shows the total number of publications written about "Genes, myc" by people in this website by year, and whether "Genes, myc" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Genes, myc" by people in Profiles.
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Trichodermin Induces G0/G1 Cell Cycle Arrest by Inhibiting c-Myc in Ovarian Cancer Cells and Tumor Xenograft-Bearing Mice. Int J Mol Sci. 2021 May 09; 22(9).
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Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models. BMC Cancer. 2018 Dec 10; 18(1):1233.
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Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. Sci Data. 2016 Feb 16; 3:160008.
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An epigenetic auto-feedback loop regulates TGF-? type II receptor expression and function in NSCLC. Oncotarget. 2015 Oct 20; 6(32):33237-52.
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Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model. Mol Cancer Ther. 2013 Jun; 12(6):1140-50.
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MYC and EIF3H Coamplification significantly improve response and survival of non-small cell lung cancer patients (NSCLC) treated with gefitinib. J Thorac Oncol. 2009 Apr; 4(4):472-8.
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Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res. 2008 Feb 01; 68(3):937-45.
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Heterogeneity in retinoic acid signaling in neuroblastomas: Role of matrix metalloproteinases in retinoic acid-induced differentiation. Biochim Biophys Acta. 2007 Sep; 1772(9):1093-102.
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RAS, MYC, and sensitivity to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis. Cancer Res. 2005 Feb 15; 65(4):1615-6; author reply 1616-7.
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Quantitation of gene-specific DNA damage by competitive PCR. Anal Biochem. 2002 Jul 15; 306(2):212-21.