11-beta-Hydroxysteroid Dehydrogenase Type 2

"11-beta-Hydroxysteroid Dehydrogenase Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An high-affinity, NAD-dependent 11-beta-hydroxysteroid dehydrogenase that acts unidirectionally to catalyze the dehydrogenation of CORTISOL to CORTISONE. It is found predominantly in mineralocorticoid target tissues such as the KIDNEY; COLON; SWEAT GLANDS; and the PLACENTA. Absence of the enzyme leads to a fatal form of childhood hypertension termed, APPARENT MINERALOCORTICOID EXCESS SYNDROME.


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This graph shows the total number of publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 2" by people in this website by year, and whether "11-beta-Hydroxysteroid Dehydrogenase Type 2" was a major or minor topic of these publications.
Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2001 and 2004 and 2016 and 2017 and 2019
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