"Pentobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
| Descriptor ID |
D010424
|
| MeSH Number(s) |
D03.383.742.698.253.593
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentobarbital".
Below are MeSH descriptors whose meaning is more specific than "Pentobarbital".
This graph shows the total number of publications written about "Pentobarbital" by people in this website by year, and whether "Pentobarbital" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentobarbital" by people in Profiles.
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Comparisons of a2-Adrenergic Agents, Medetomidine and Xylazine, with Pentobarbital for Anesthesia: Important Pitfalls in Diabetic and Nondiabetic Rats. J Ocul Pharmacol Ther. 2022 03; 38(2):156-166.
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Pentobarbital coma for refractory intra-cranial hypertension after severe traumatic brain injury: mortality predictions and one-year outcomes in 55 patients. J Trauma. 2010 Aug; 69(2):275-83.
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Activation of alpha6-containing GABAA receptors by pentobarbital occurs through a different mechanism than activation by GABA. Neurosci Lett. 2010 Mar 08; 471(3):195-9.
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Evaluation of feeding intolerance in patients with pentobarbital-induced coma. Ann Pharmacother. 2008 Apr; 42(4):516-22.
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Identification of structures within GABAA receptor alpha subunits that regulate the agonist action of pentobarbital. J Pharmacol Exp Ther. 2006 Sep; 318(3):1094-101.
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Full neurologic recovery after fulminant thrombotic thrombocytopenic purpura with status epilepticus. Seizure. 2004 Dec; 13(8):549-52.
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Amiloride inhibition of gamma-aminobutyric acid(A) receptors depends upon the alpha subunit subtype. Mol Pharmacol. 2002 Jun; 61(6):1322-8.
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Modulation of ornithine decarboxylase mRNA following transient ischemia in the gerbil brain. J Cereb Blood Flow Metab. 1991 Nov; 11(6):979-85.
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Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine. Lab Anim Sci. 1986 Aug; 36(4):357-61.
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Dopamine reverses cardiovascular depression of toxic doses of pentobarbitone in dogs. Can Anaesth Soc J. 1984 Nov; 31(6):654-8.