"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
| Descriptor ID |
D010634
|
| MeSH Number(s) |
D03.383.742.698.253.650
|
| Concept/Terms |
Phenobarbital- Phenobarbital
- Phenylbarbital
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenobarbitone
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
|
Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Phenobarbital" by people in Profiles.
-
Co-induction of glutathione-S-transferases and multidrug resistance associated protein by xenobiotics in wheat. Pest Manag Sci. 2003 Feb; 59(2):202-14.
-
Benzodiazepine dependence and withdrawal: identification and medical management. J Am Board Fam Pract. 1992 Mar-Apr; 5(2):167-75.
-
Immunochromatographic measurement of phenobarbital in whole blood with a non-instrumented assay. Neurology. 1989 Sep; 39(9):1215-8.
-
Phenobarbital during pregnancy in mouse and man. Neurotoxicology. 1986; 7(2):287-301.
-
[Teratogenic effects of anticonvulsants with the development of multiple congenital anomalies - report on 3 patients]. Lijec Vjesn. 1983 May; 105(5):191-4.
-
Pregnancy increases reactivity of mice to phenobarbital. Science. 1983 Apr 29; 220(4596):534-6.
-
Brain concentrations of phenobarbital and behavioral activation or depression. Pharmacol Biochem Behav. 1981 Nov; 15(5):723-8.
-
Effects of prenatal maternal injections of phenobarbital on brain neurotransmitters and behavior of young C57 mice. Neurobehav Toxicol Teratol. 1981; 3(3):271-5.
-
Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli. Psychopharmacology (Berl). 1981; 74(4):349-52.
-
Failure of muscarinic blockade to antagonize analepsis induced by thyrotropin-releasing hormone and MK-771 in the rat. Psychopharmacology (Berl). 1981; 74(1):13-6.