"Phosphodiesterase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis.
| Descriptor ID |
D043264
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| MeSH Number(s) |
D08.811.277.352.640.430
|
| Concept/Terms |
Phosphodiesterase I- Phosphodiesterase I
- Orthophosphoric Diester Phosphohydrolase
- Diester Phosphohydrolase, Orthophosphoric
- Phosphohydrolase, Orthophosphoric Diester
- Alkaline Phosphodiesterase I
- Phosphodiesterase I, Alkaline
- 5'-Nucleotidephosphodiesterase
- 5' Nucleotidephosphodiesterase
- Alkaline Phosphodiesterase
- Phosphodiesterase, Alkaline
- Oligonucleate 5'-Nucleotidohydrolase
- Oligonucleate 5' Nucleotidohydrolase
- 5'-Exonuclease
- 5' Exonuclease
|
Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase I".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase I".
This graph shows the total number of publications written about "Phosphodiesterase I" by people in this website by year, and whether "Phosphodiesterase I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphodiesterase I" by people in Profiles.
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BK channel regulation by phosphodiesterase type 1: a novel signaling pathway controlling human detrusor smooth muscle function. Am J Physiol Renal Physiol. 2016 05 15; 310(10):F994-9.
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Rapid identification of up to three Candida species in a single reaction tube by a 5' exonuclease assay using fluorescent DNA probes. J Clin Microbiol. 1999 Jan; 37(1):165-70.
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Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines. Chem Biol Interact. 1985 Jul; 54(2):209-22.