"Phospholipases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
| Descriptor ID |
D010740
|
| MeSH Number(s) |
D08.811.277.352.100.680 D08.811.277.352.640.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phospholipases".
Below are MeSH descriptors whose meaning is more specific than "Phospholipases".
This graph shows the total number of publications written about "Phospholipases" by people in this website by year, and whether "Phospholipases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phospholipases" by people in Profiles.
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Bioactive sphingolipids: metabolism and function. J Lipid Res. 2009 Apr; 50 Suppl:S91-6.
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Proteases and phospholipases in CNS disorders. CNS Neurol Disord Drug Targets. 2008 Jun; 7(3):225-6.
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Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding. J Lipid Res. 2007 Oct; 48(10):2306-18.
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The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae. J Biol Chem. 2005 Feb 25; 280(8):7170-7.
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Activation and localization of inositol phosphosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharomyces cerevisiae. J Biol Chem. 2004 Mar 19; 279(12):11537-45.
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Functional analysis of ISC1 by site-directed mutagenesis. Biochemistry. 2003 Jul 01; 42(25):7855-62.
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Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism. J Biol Chem. 2003 Apr 18; 278(16):13775-83.
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Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem. 2000 Dec 15; 275(50):39793-8.
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Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem J. 1995 Apr 01; 307 ( Pt 1):99-106.
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Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. Res Commun Chem Pathol Pharmacol. 1992 Oct; 78(1):27-38.