Hydroxymethylglutaryl-CoA Synthase
"Hydroxymethylglutaryl-CoA Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
Descriptor ID |
D006904
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MeSH Number(s) |
D08.811.913.050.612
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Concept/Terms |
Hydroxymethylglutaryl-CoA Synthase- Hydroxymethylglutaryl-CoA Synthase
- Hydroxymethylglutaryl CoA Synthase
- Synthase, Hydroxymethylglutaryl-CoA
- 3-hydroxy-3-methylglutaryl-coenzyme A synthase
- HMG-CoA synthase
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Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Synthase".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Synthase".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA Synthase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in Profiles.
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Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells. Biochim Biophys Acta. 2004 Jul 05; 1683(1-3):89-100.
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Further characterization of a somatic cell mutant defective in regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Somat Cell Mol Genet. 1988 Nov; 14(6):527-39.