"Citrate (si)-Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
| Descriptor ID |
D002950
|
| MeSH Number(s) |
D08.811.913.050.368
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Citrate (si)-Synthase".
Below are MeSH descriptors whose meaning is more specific than "Citrate (si)-Synthase".
This graph shows the total number of publications written about "Citrate (si)-Synthase" by people in this website by year, and whether "Citrate (si)-Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Citrate (si)-Synthase" by people in Profiles.
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Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle. Antioxid Redox Signal. 2014 Nov 10; 21(14):1974-85.
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Cardiac subsarcolemmal and interfibrillar mitochondria display distinct responsiveness to protection by diazoxide. PLoS One. 2012; 7(9):e44667.
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Potential importance of glomerular citrate synthase activity in remnant nephropathy. Kidney Int. 2003 Jan; 63(1):156-64.
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Role of citrate synthase in aldosterone-mediated sodium reabsorption. Hypertension. 2000 Apr; 35(4):875-9.
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Resistance to mineralocorticoids in Wistar-Furth rats. Am J Physiol. 1997 Mar; 272(3 Pt 2):H1454-61.
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Changes in the growth hormone axis due to exercise training in male and female rats: secretory and molecular responses. Endocrinology. 1995 Jun; 136(6):2664-70.
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A new mtDNA mutation in the tRNA(Leu(UUR)) gene associated with maternally inherited cardiomyopathy. Hum Mutat. 1994; 3(1):37-43.
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Clinical features associated with the A-->G transition at nucleotide 8344 of mtDNA ("MERRF mutation"). Neurology. 1993 Jun; 43(6):1200-6.