"Oligomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
| Descriptor ID |
D009840
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| MeSH Number(s) |
D02.540.505.620
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligomycins".
Below are MeSH descriptors whose meaning is more specific than "Oligomycins".
This graph shows the total number of publications written about "Oligomycins" by people in this website by year, and whether "Oligomycins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oligomycins" by people in Profiles.
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ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition. Am J Physiol. 1994 Jul; 267(1 Pt 1):C67-74.
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Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine. J Pharmacol Exp Ther. 1993 Apr; 265(1):392-400.
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Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am J Physiol. 1993 Apr; 264(4 Pt 1):C961-7.
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Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta. 1986 Jul 23; 850(3):436-48.
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Non-equilibrium thermodynamics of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria. J Biol Chem. 1981 Dec 25; 256(24):12949-57.
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Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumor cell. J Cell Biol. 1971 Oct; 51(1):123-37.