"Pyridoxal Phosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
| Descriptor ID |
D011732
|
| MeSH Number(s) |
D03.383.725.676.925.500.500 D08.211.740
|
| Concept/Terms |
Pyridoxal Phosphate- Pyridoxal Phosphate
- Phosphate, Pyridoxal
- Pyridoxal-P
- Pyridoxal P
- Pyridoxal 5-Phosphate
- Pyridoxal 5 Phosphate
|
Below are MeSH descriptors whose meaning is more general than "Pyridoxal Phosphate".
Below are MeSH descriptors whose meaning is more specific than "Pyridoxal Phosphate".
This graph shows the total number of publications written about "Pyridoxal Phosphate" by people in this website by year, and whether "Pyridoxal Phosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
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Below are the most recent publications written about "Pyridoxal Phosphate" by people in Profiles.
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Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial. JAMA. 2008 Apr 16; 299(15):1777-87.
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A randomized, double-blind, placebo-controlled, multicenter study to evaluate the cardioprotective effects of MC-1 in patients undergoing high-risk coronary artery bypass graft surgery: MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery Trial (MEND-CABG) II--study design and rationale. Am Heart J. 2008 Apr; 155(4):600-8.
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Effects of pyridoxal-5'-phosphate (MC-1) in patients undergoing high-risk coronary artery bypass surgery: results of the MEND-CABG randomized study. J Thorac Cardiovasc Surg. 2007 Jun; 133(6):1604-11.
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MC-1 (pyridoxal 5'-phosphate): novel therapeutic applications to reduce ischaemic injury. Expert Opin Investig Drugs. 2005 Nov; 14(11):1435-42.
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Reduction of myocardial ischemic injury following coronary intervention (the MC-1 to Eliminate Necrosis and Damage trial). Am J Cardiol. 2003 Sep 15; 92(6):660-4.
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Plasma pyridoxal phosphate in anxiety disorders. Biol Psychiatry. 1994 Nov 01; 36(9):606-8.
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Phenelzine treatment of panic disorder: lack of effect on pyridoxal phosphate levels. J Clin Psychopharmacol. 1989 Dec; 9(6):428-31.
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Fluorescence lifetime and polarization anisotropy studies of membrane surfaces with pyridoxal 5'-phosphate. Biophys Chem. 1987 Dec; 28(3):265-71.
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The metabolism of gamma-aminobutyric acid (GABA) in the lobster nervous system--glutamic decarboxylase. J Neurochem. 1968 May; 15(5):391-409.