"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
|
| MeSH Number(s) |
G05.308.203.374
|
| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
|
Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 3 | 4 |
| 2006 | 2 | 6 | 8 |
| 2007 | 3 | 5 | 8 |
| 2008 | 1 | 8 | 9 |
| 2009 | 5 | 7 | 12 |
| 2010 | 2 | 5 | 7 |
| 2011 | 2 | 3 | 5 |
| 2012 | 1 | 10 | 11 |
| 2013 | 2 | 4 | 6 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 6 | 7 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 3 | 6 |
| 2018 | 1 | 3 | 4 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 4 | 4 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Inclisiran: a small interfering RNA strategy targeting PCSK9 to treat hypercholesterolemia. Expert Opin Drug Saf. 2022 Jan; 21(1):9-20.
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Modulation of p75NTR on Mesenchymal Stem Cells Increases Their Vascular Protection in Retinal Ischemia-Reperfusion Mouse Model. Int J Mol Sci. 2021 Jan 15; 22(2).
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An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction. Life Sci. 2020 Oct 15; 259:118199.
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FMR1 mRNA from full mutation alleles is associated with ABC-CFX scores in males with fragile X syndrome. Sci Rep. 2020 07 16; 10(1):11701.
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ATF3 Coordinates Antitumor Synergy between Epigenetic Drugs and Protein Disulfide Isomerase Inhibitors. Cancer Res. 2020 08 15; 80(16):3279-3291.
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PRDM16 suppresses HIF-targeted gene expression in kidney cancer. J Exp Med. 2020 06 01; 217(6).
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A cationic amphiphilic co-polymer as a carrier of nucleic acid nanoparticles (Nanps) for controlled gene silencing, immunostimulation, and biodistribution. Nanomedicine. 2020 01; 23:102094.
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Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis. Cell Rep. 2018 12 11; 25(11):3036-3046.e6.
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LncRNA-135528 inhibits tumor progression by up-regulating CXCL10 through the JAK/STAT pathway. Apoptosis. 2018 12; 23(11-12):651-666.
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A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis in Drosophila. J Biol Chem. 2018 06 15; 293(24):9140-9147.