"TRPV Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.
| Descriptor ID |
D050916
|
| MeSH Number(s) |
D12.776.157.530.400.901.888
|
| Concept/Terms |
TRPV Cation Channels- TRPV Cation Channels
- Cation Channels, TRPV
- Channels, TRPV Cation
- Capsaicin Receptors
- Receptors, Capsaicin
- Vanilloid Receptors
- Receptors, Vanilloid
|
Below are MeSH descriptors whose meaning is more general than "TRPV Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPV Cation Channels".
This graph shows the total number of publications written about "TRPV Cation Channels" by people in this website by year, and whether "TRPV Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPV Cation Channels" by people in Profiles.
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Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats. JCI Insight. 2022 09 22; 7(18).
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Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis. Pediatr Cardiol. 2020 Dec; 41(8):1675-1688.
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Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct. Am J Physiol Renal Physiol. 2019 09 01; 317(3):F632-F637.
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Novel Potentials of the DPP-4 Inhibitor Sitagliptin against Ischemia-Reperfusion (I/R) Injury in Rat Ex-Vivo Heart Model. Int J Mol Sci. 2018 Oct 18; 19(10).
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Muscarinic M1 Receptor Modulation of Synaptic Plasticity in Nucleus Accumbens of Wild-Type and Fragile X Mice. ACS Chem Neurosci. 2018 09 19; 9(9):2233-2240.
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TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. Free Radic Biol Med. 2017 01; 102:260-273.
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Tear gas: an epidemiological and mechanistic reassessment. Ann N Y Acad Sci. 2016 08; 1378(1):96-107.
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Pancreatic pain. Curr Opin Gastroenterol. 2015 Sep; 31(5):407-15.
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Endocannabinoid modulation of cortical up-states and NREM sleep. PLoS One. 2014; 9(2):e88672.
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TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLoS One. 2013; 8(8):e73424.