"Diethylstilbestrol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
| Descriptor ID |
D004054
|
| MeSH Number(s) |
D02.455.426.559.389.150.700.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Diethylstilbestrol".
Below are MeSH descriptors whose meaning is more specific than "Diethylstilbestrol".
This graph shows the total number of publications written about "Diethylstilbestrol" by people in this website by year, and whether "Diethylstilbestrol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diethylstilbestrol" by people in Profiles.
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Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation. Toxicology. 2018 12 01; 410:49-58.
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Exposure to diethylstilbestrol during pregnancy modulates microRNA expression profile in mothers and fetuses reflecting oncogenic and immunological changes. Mol Pharmacol. 2015 May; 87(5):842-54.
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs. J Pharmacol Exp Ther. 2012 Nov; 343(2):351-61.
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Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol. Int J Toxicol. 2006 Jan-Feb; 25(1):9-15.
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Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery. Toxicol Appl Pharmacol. 2006 Apr 15; 212(2):119-26.
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Critical evaluation of hormonal therapy for carcinoma of the prostate. Urology. 2002 Aug; 60(2):201-8.
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Estrogens and environmental estrogens. Biomed Pharmacother. 2002 Feb; 56(1):36-44.
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Single-therapy androgen suppression in men with advanced prostate cancer: a systematic review and meta-analysis. Ann Intern Med. 2000 Apr 04; 132(7):566-77.
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Glutathione S-transferase in hormonal carcinogenesis. Chem Biol Interact. 1998 Apr 24; 111-112:343-50.
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Treatment of endometriosis. Am J Obstet Gynecol. 1986 Jan; 154(1):215-6.