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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.

Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. Mol Cancer. 2007 Jul 10; 6:46.

View in: PubMed

subject areas
  • Aminoimidazole Carboxamide
  • AMP-Activated Protein Kinases
  • Antineoplastic Agents
  • Apoptosis
  • Cell Division
  • DNA Replication
  • Drug Delivery Systems
  • Drug Resistance, Neoplasm
  • Drug Screening Assays, Antitumor
  • Enzyme Activation
  • G1 Phase
  • Humans
  • Imidazoles
  • Leukemia-Lymphoma, Adult T-Cell
  • Multienzyme Complexes
  • Neoplasm Proteins
  • p38 Mitogen-Activated Protein Kinases
  • Phosphorylation
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Prodrugs
  • Protein Processing, Post-Translational
  • Proto-Oncogene Proteins c-akt
  • Pyridines
  • Ribonucleotides
  • Sirolimus
  • Tubercidin
  • Tumor Cells, Cultured

authors with profiles
  • Inderjit Singh