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Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line.

Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line. J Biol Chem. 2001 Aug 31; 276(35):32506-14.

View in: PubMed

subject areas
  • Adenocarcinoma
  • Ceramides
  • Cycloheximide
  • DNA-Binding Proteins
  • Gene Expression Regulation, Enzymologic
  • Gene Expression Regulation, Neoplastic
  • Genes, myc
  • Genes, Reporter
  • Half-Life
  • Humans
  • Luciferases
  • Lung Neoplasms
  • Promoter Regions, Genetic
  • Proto-Oncogene Proteins c-myc
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA, Messenger
  • Telomerase
  • Transcription, Genetic
  • Transfection
  • Tumor Cells, Cultured
  • Ubiquitins

authors with profiles
  • Besim Ogretmen
  • Jacqueline M Kraveka
  • Yusuf A. Hannun