7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.

7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors. J Pharmacol Exp Ther. 1992 Aug; 262(2):632-7.

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subject areas

Binding, Competitive
Blood Platelets
Bridged Bicyclo Compounds
Bridged Bicyclo Compounds, Heterocyclic
Fatty Acids, Monounsaturated
Fatty Acids, Unsaturated
Humans
Hydrogen-Ion Concentration
Platelet Aggregation
Platelet Aggregation Inhibitors
Prostaglandin Endoperoxides, Synthetic
Receptors, Prostaglandin
Receptors, Thromboxane
Receptors, Thromboxane A2, Prostaglandin H2
Thromboxane A2

authors with profiles

Perry V. Halushka