Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity.

Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. J Pharmacol Exp Ther. 2005 Nov; 315(2):879-87.

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subject areas

Acetaminophen
Analgesics, Non-Narcotic
Animals
Apoptosis
Cell Nucleus
Chemical and Drug Induced Liver Injury
DNA Damage
DNA Fragmentation
DNA, Mitochondrial
Endonucleases
In Situ Hybridization
In Situ Nick-End Labeling
Male
Mice
Mice, Inbred C3H
Mitochondria, Liver
Peroxynitrous Acid
Subcellular Fractions
Tumor Necrosis Factor-alpha

authors with profiles

John J. Lemasters