"DNA Fragmentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.
| Descriptor ID |
D053938
|
| MeSH Number(s) |
G05.200.230
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "DNA Fragmentation".
Below are MeSH descriptors whose meaning is more specific than "DNA Fragmentation".
This graph shows the total number of publications written about "DNA Fragmentation" by people in this website by year, and whether "DNA Fragmentation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 5 | 5 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 5 | 5 |
| 2007 | 2 | 5 | 7 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 3 | 4 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "DNA Fragmentation" by people in Profiles.
-
DNA methylation patterns vary in boar sperm cells with different levels of DNA fragmentation. BMC Genomics. 2019 Nov 27; 20(1):897.
-
Endoplasmic reticulum stress, autophagic and apoptotic cell death, and immune activation by a natural triterpenoid in human prostate cancer cells. J Cell Biochem. 2019 04; 120(4):6264-6276.
-
Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing. Methods Mol Biol. 2018; 1803:209-230.
-
A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/?-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34.
-
Comparison of custom capture for targeted next-generation DNA sequencing. J Mol Diagn. 2015 Jan; 17(1):64-75.
-
Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma. Oncotarget. 2014 Nov 30; 5(22):11709-22.
-
Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci. 2011 Aug; 122(2):598-605.
-
Pathogenesis, developmental consequences, and clinical correlations of human embryo fragmentation. Fertil Steril. 2011 Mar 15; 95(4):1197-204.
-
Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury. Free Radic Res. 2011 Feb; 45(2):156-64.
-
Combined anticancer effects of sphingosine kinase inhibitors and sorafenib. Invest New Drugs. 2011 Dec; 29(6):1132-42.