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    • Adverse left ventricular remodeling in community-dwelling older adults predicts incident heart failure and mortality.
    • Differential abundance of CK1a provides selectivity for pharmacological CK1a activators to target WNT-dependent tumors.
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Differential abundance of CK1a provides selectivity for pharmacological CK1a activators to target WNT-dependent tumors.

Differential abundance of CK1a provides selectivity for pharmacological CK1a activators to target WNT-dependent tumors. Sci Signal. 2017 Jun 27; 10(485).

View in: PubMed

subject areas
  • Animals
  • Antineoplastic Agents
  • Benzoates
  • Casein Kinase Ialpha
  • Enzyme Activation
  • Enzyme Activators
  • Gene Expression Regulation, Neoplastic
  • HCT116 Cells
  • Humans
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Mice, Nude
  • Neoplasm Metastasis
  • Neoplasms
  • Organ Culture Techniques
  • Phosphorylation
  • Pyrvinium Compounds
  • Signal Transduction
  • Surface Plasmon Resonance
  • Wnt Proteins
  • Wnt Signaling Pathway
  • Xenograft Model Antitumor Assays
  • Xenopus laevis

authors with profiles
  • Jezabel Rodriguez-Blanco