"Casein Kinase Ialpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A casein kinase I isoenzyme that plays a role in intracellular signaling pathways including the WNT SIGNALING PATHWAY, the CELL CYCLE, membrane trafficking, and RNA processing. Multiple isoforms of casein kinase I alpha exist and are due to ALTERNATIVE SPLICING.
| Descriptor ID |
D048128
|
| MeSH Number(s) |
D05.500.117.750.100 D08.811.913.696.620.682.700.140.300.100 D12.776.476.081.750.100 D12.776.476.150.299.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase Ialpha".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase Ialpha".
This graph shows the total number of publications written about "Casein Kinase Ialpha" by people in this website by year, and whether "Casein Kinase Ialpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Casein Kinase Ialpha" by people in Profiles.
-
A CK1a Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma. Clin Cancer Res. 2019 02 15; 25(4):1379-1388.
-
Differential abundance of CK1a provides selectivity for pharmacological CK1a activators to target WNT-dependent tumors. Sci Signal. 2017 Jun 27; 10(485).
-
Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Res. 2014 Sep 01; 74(17):4811-21.