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    • The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction.
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    • Evidence for prostacyclin and cAMP upregulation by bradykinin and insulin-like growth factor 1 in vascular smooth muscle cells.
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Evidence for prostacyclin and cAMP upregulation by bradykinin and insulin-like growth factor 1 in vascular smooth muscle cells.

Evidence for prostacyclin and cAMP upregulation by bradykinin and insulin-like growth factor 1 in vascular smooth muscle cells. J Recept Signal Transduct Res. 2010 Apr; 30(2):61-71.

View in: PubMed

subject areas
  • Animals
  • Blotting, Western
  • Bradykinin
  • Cells, Cultured
  • Cyclic AMP
  • Epoprostenol
  • Group IV Phospholipases A2
  • Insulin-Like Growth Factor I
  • Male
  • Mitogen-Activated Protein Kinase 1
  • Mitogen-Activated Protein Kinase 3
  • Muscle, Smooth, Vascular
  • Prostaglandin-Endoperoxide Synthases
  • Proto-Oncogene Proteins c-fos
  • Rats
  • Rats, Sprague-Dawley
  • Receptor, IGF Type 1
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA, Messenger
  • Signal Transduction
  • Up-Regulation
  • Vasodilator Agents

authors with profiles
  • Miran A. Jaffa
  • Ayad A. Jaffa
  • Jerry Glenn Webb