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Inhibition of RAS: proven and potential vulnerabilities.

Inhibition of RAS: proven and potential vulnerabilities. Biochem Soc Trans. 2020 10 30; 48(5):1831-1841.

View in: PubMed

subject areas
  • Acetonitriles
  • Allosteric Regulation
  • Allosteric Site
  • Animals
  • Antineoplastic Agents
  • Catalytic Domain
  • Cell Membrane
  • Dimerization
  • Drug Design
  • GTP Phosphohydrolases
  • Humans
  • Metabolism
  • Mice
  • Molecular Conformation
  • Mutation
  • Neoplasm Transplantation
  • Neoplasms
  • Piperazines
  • Protein Conformation
  • Proto-Oncogene Proteins p21(ras)
  • Pyridines
  • Pyrimidines
  • ras Proteins
  • Signal Transduction

authors with profiles
  • Imran Khan
  • John P. O'Bryan
  • Mariyam Zuberi