Kininogen, High-Molecular-Weight

"Kininogen, High-Molecular-Weight" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)


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This graph shows the total number of publications written about "Kininogen, High-Molecular-Weight" by people in this website by year, and whether "Kininogen, High-Molecular-Weight" was a major or minor topic of these publications.
Bar chart showing 21 publications over 13 distinct years, with a maximum of 3 publications in 1999 and 2003
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