Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors.
| Descriptor ID |
D064191
|
| MeSH Number(s) |
D08.811.464.938.750.092.875 D12.776.167.024.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome".
Below are MeSH descriptors whose meaning is more specific than "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome".
This graph shows the total number of publications written about "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in this website by year, and whether "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome" by people in Profiles.
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PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27. Mol Cancer Res. 2016 07; 14(7):634-46.
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Regulation of Skp2 levels by the Pim-1 protein kinase. J Biol Chem. 2010 Sep 17; 285(38):29128-37.