ATP Binding Cassette Transporter 1
"ATP Binding Cassette Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.
| Descriptor ID |
D064286
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| MeSH Number(s) |
D12.776.157.530.100.190.500 D12.776.395.550.020.381.500 D12.776.543.550.192.381.500 D12.776.543.585.100.190.500
|
| Concept/Terms |
ATP Binding Cassette Transporter 1- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Sub-Family A Member 1
- ATP Binding Cassette Sub Family A Member 1
- CERP Protein
- Protein, CERP
- ABCA1 Protein
- Protein, ABCA1
- Cholesterol-Efflux Regulatory Protein
- Cholesterol Efflux Regulatory Protein
- Protein, Cholesterol-Efflux Regulatory
- Regulatory Protein, Cholesterol-Efflux
|
Below are MeSH descriptors whose meaning is more general than "ATP Binding Cassette Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "ATP Binding Cassette Transporter 1".
This graph shows the total number of publications written about "ATP Binding Cassette Transporter 1" by people in this website by year, and whether "ATP Binding Cassette Transporter 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "ATP Binding Cassette Transporter 1" by people in Profiles.
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NNMT contributes to high metastasis of triple negative breast cancer by enhancing PP2A/MEK/ERK/c-Jun/ABCA1 pathway mediated membrane fluidity. Cancer Lett. 2022 10 28; 547:215884.
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Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020 01 08; 28(1):202-216.
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ATP binding cassette family A protein 1 determines hexosylceramide and sphingomyelin levels in human and mouse plasma. J Lipid Res. 2018 11; 59(11):2084-2097.
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LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo. Arterioscler Thromb Vasc Biol. 2018 05; 38(5):1191-1201.
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ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion. EBioMedicine. 2017 Apr; 18:139-145.
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Ursolic acid enhances macrophage autophagy and attenuates atherogenesis. J Lipid Res. 2016 06; 57(6):1006-16.
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Lipid-free apolipoprotein A-I and discoidal reconstituted high-density lipoproteins differentially inhibit glucose-induced oxidative stress in human macrophages. Arterioscler Thromb Vasc Biol. 2011 May; 31(5):1192-200.
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Modulation of ABCA1 by an LXR agonist reduces ?-amyloid levels and improves outcome after traumatic brain injury. J Neurotrauma. 2011 Feb; 28(2):225-36.
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Adiponectin reduces lipid accumulation in macrophage foam cells. Atherosclerosis. 2009 Jan; 202(1):152-61.
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Impaired secretion of apolipoprotein E2 from macrophages. J Biol Chem. 2007 May 04; 282(18):13746-53.