"Emodin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Purgative anthraquinone found in several plants, especially Rhamnus frangula. It was formerly used as a laxative, but is now used mainly as tool in toxicity studies.
| Descriptor ID |
D004642
|
| MeSH Number(s) |
D02.455.426.559.847.117.159.205.400 D02.806.100.205.400 D04.615.117.159.205.400
|
| Concept/Terms |
Emodin- Emodin
- Rheum Emodin
- Emodin, Rheum
- Frangulic Acid
- Archin
- Frangula Emodin
- Emodin, Frangula
|
Below are MeSH descriptors whose meaning is more general than "Emodin".
Below are MeSH descriptors whose meaning is more specific than "Emodin".
This graph shows the total number of publications written about "Emodin" by people in this website by year, and whether "Emodin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Emodin" by people in Profiles.
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Emodin reduces tumor burden by diminishing M2-like macrophages in colorectal cancer. Am J Physiol Gastrointest Liver Physiol. 2022 03 01; 322(3):G383-G395.
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Therapeutic Potential of Emodin for Gastrointestinal Cancers. Integr Cancer Ther. 2022 Jan-Dec; 21:15347354211067469.
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Effects of emodin, a plant-derived anthraquinone, on TGF-?1-induced cardiac fibroblast activation and function. J Cell Physiol. 2021 11; 236(11):7440-7449.
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Safety of natural anthraquinone emodin: an assessment in mice. BMC Pharmacol Toxicol. 2021 01 28; 22(1):9.
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Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation. Theranostics. 2020; 10(18):8365-8381.
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Anticancer activity of emodin is associated with downregulation of CD155. Int Immunopharmacol. 2019 Oct; 75:105763.
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Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages. Mol Cancer Ther. 2016 08; 15(8):1931-42.
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Emodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory. J Biol Chem. 2016 May 27; 291(22):11491-503.
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Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs. Breast Cancer Res Treat. 2014 Nov; 148(2):291-302.