"Caspases, Initiator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of caspases that contain long pro-domain regions that regulate the activation of the enzyme. The pro-domain regions contain protein-protein interaction motifs that can interact with specific signaling adaptor proteins such as DEATH DOMAIN RECEPTORS; DED SIGNALING ADAPTOR PROTEINS; and CARD SIGNALING ADAPTOR PROTEINS. Once activated, the initiator caspases can activate other caspases such as the EFFECTOR CASPASES.
| Descriptor ID |
D053471
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550 D08.811.277.656.300.200.126.550 D12.644.360.075.405.550 D12.776.476.075.405.550
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspases, Initiator".
Below are MeSH descriptors whose meaning is more specific than "Caspases, Initiator".
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