"Cysteine Endopeptidases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.
| Descriptor ID |
D003546
|
| MeSH Number(s) |
D08.811.277.656.262.500 D08.811.277.656.300.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cysteine Endopeptidases".
Below are MeSH descriptors whose meaning is more specific than "Cysteine Endopeptidases".
This graph shows the total number of publications written about "Cysteine Endopeptidases" by people in this website by year, and whether "Cysteine Endopeptidases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 2 | 0 | 2 |
| 1997 | 2 | 1 | 3 |
| 1998 | 2 | 1 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 4 | 0 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cysteine Endopeptidases" by people in Profiles.
-
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design. Sci Adv. 2020 10; 6(42).
-
An intramembrane sensory circuit monitors sortase A-mediated processing of streptococcal adhesins. Sci Signal. 2019 05 07; 12(580).
-
Directed evolution provides insight into conformational substrate sampling by SrtA. PLoS One. 2017; 12(8):e0184271.
-
Structure and specificity of a new class of Ca2+-independent housekeeping sortase from Streptomyces avermitilis provide insights into its non-canonical substrate preference. J Biol Chem. 2017 04 28; 292(17):7244-7257.
-
CHK1 regulates NF-?B signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles. Oncotarget. 2016 Apr 05; 7(14):18159-70.
-
Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2. J Mol Cell Cardiol. 2015 Jul; 84:143-53.
-
A pro-inflammatory role of deubiquitinating enzyme cylindromatosis (CYLD) in vascular smooth muscle cells. Biochem Biophys Res Commun. 2012 Mar 30; 420(1):78-83.
-
Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells. Brain Res. 2009 Aug 04; 1283:155-66.
-
Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell. 2008 Oct; 7(5):609-21.
-
La autoantigen suppresses IRES-dependent translation of the hepatitis A virus. Biochem Biophys Res Commun. 2008 Apr 18; 368(4):1014-9.