"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
|
| MeSH Number(s) |
G05.308.207
|
| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
|
Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 1 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 2 | 3 |
| 2015 | 2 | 2 | 4 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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IGHG, IGKC, and FCGR genes and endogenous antibody responses to GARP in patients with breast cancer and matched controls. Hum Immunol. 2018 Aug; 79(8):632-637.
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Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiol Aging. 2016 Feb; 38:141-150.
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Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk. Alzheimers Dement. 2016 Feb; 12(2):121-129.
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NK Cell and Ig Interplay in Defense against Herpes Simplex Virus Type 1: Epistatic Interaction of CD16A and IgG1 Allotypes of Variable Affinities Modulates Antibody-Dependent Cellular Cytotoxicity and Susceptibility to Clinical Reactivation. J Immunol. 2015 Aug 15; 195(4):1676-84.
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The role of base excision repair in the development of primary open angle glaucoma in the Polish population. Mutat Res. 2015 Aug; 778:26-40.
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A Pkd1-Fbn1 genetic interaction implicates TGF-? signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2014 Jan; 25(1):81-91.
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Suggestive evidence that Fc variants of IgG2 and Fc?RIIa loci interact to contribute to the risk of prostate cancer. Hum Immunol. 2013 Dec; 74(12):1656-8.
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Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Transl Psychiatry. 2013 May 14; 3:e256.
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LBoost: A boosting algorithm with application for epistasis discovery. PLoS One. 2012; 7(11):e47281.
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Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus. Arthritis Rheum. 2012 Feb; 64(2):485-92.