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    • Johnson, Eric
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    • PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.

View in: PubMed

subject areas
  • Animals
  • Antineoplastic Agents
  • Arginine
  • Biocatalysis
  • Breast Neoplasms
  • Carcinogenesis
  • Cell Line, Tumor
  • Cell Membrane
  • Cell Proliferation
  • Enzyme Activation
  • Female
  • HEK293 Cells
  • Humans
  • Methylation
  • Mice, Nude
  • Mutation
  • Protein Binding
  • Protein Kinase Inhibitors
  • Protein-Arginine N-Methyltransferases
  • Proto-Oncogene Proteins c-akt
  • RNA, Small Interfering
  • Signal Transduction

authors with profiles
  • Lauren Elizabeth Ball
  • Viswanathan Palanisamy
  • Shaun K. Olsen
  • Michael C Ostrowski
  • Wenjian Gan
  • Shasha Yin