Receptor, Serotonin, 5-HT2A
"Receptor, Serotonin, 5-HT2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.
| Descriptor ID |
D044402
|
| MeSH Number(s) |
D12.776.543.750.670.800.200.100 D12.776.543.750.695.800.200.100 D12.776.543.750.720.850.200.100
|
| Concept/Terms |
Receptor, Serotonin, 5-HT2A- Receptor, Serotonin, 5-HT2A
- 5-HT2A Receptor
- 5 HT2A Receptor
- Receptor, 5-HT2A
- Serotonin 2A Receptors
- Receptors, Serotonin 2A
- Serotonin 2A Receptor
- 5-HT(2A) Receptor
- Receptor, Serotonin 2A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.670.800.200.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.695.800.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.720.850.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2A" by people in Profiles.
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5-HT2 Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists. J Pharmacol Exp Ther. 2016 Apr; 357(1):1-9.
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Age, sex, and reproductive hormone effects on brain serotonin-1A and serotonin-2A receptor binding in a healthy population. Neuropsychopharmacology. 2011 Dec; 36(13):2729-40.
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5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells. J Biol Chem. 2006 Jul 28; 281(30):21004-21012.
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Brain 5-HT receptor system in the stressed infant rat: implications for vulnerability to substance abuse. Psychoneuroendocrinology. 2002 Jan-Feb; 27(1-2):245-72.
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G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells. J Biol Chem. 2001 Jul 20; 276(29):27335-44.
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5-HT(2A) receptors stimulate mitogen-activated protein kinase via H(2)O(2) generation in rat renal mesangial cells. Am J Physiol Renal Physiol. 2000 Apr; 278(4):F650-8.
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Characterization of 5-HT- and ionomycin-stimulated changes in levels of intracellular calcium and PI hydrolysis in P11 cells. Ann N Y Acad Sci. 1998 Dec 15; 861:240-1.
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Regulation of levels of 5-HT2A receptor mRNA. Ann N Y Acad Sci. 1998 Dec 15; 861:128-35.
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Identification of a rat glomerular mesangial cell mitogenic 5-HT2A receptor. Am J Physiol. 1995 Jan; 268(1 Pt 2):F122-7.