"Photoaffinity Labels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Biologically active molecules which are covalently bound to the enzymes or binding proteins normally acting on them. Binding occurs due to activation of the label by ultraviolet light. These labels are used primarily to identify binding sites on proteins.
| Descriptor ID |
D019920
|
| MeSH Number(s) |
D27.720.470.410.080.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Photoaffinity Labels".
Below are MeSH descriptors whose meaning is more specific than "Photoaffinity Labels".
This graph shows the total number of publications written about "Photoaffinity Labels" by people in this website by year, and whether "Photoaffinity Labels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Photoaffinity Labels" by people in Profiles.
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Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25; 16(9):980-9.
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Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. Biochemistry. 2006 Feb 21; 45(7):2322-32.
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Synthesis and characterization of insulin-like growth factor (IGF)-1 photoprobes selective for the IGF-binding proteins (IGFBPS). photoaffinity labeling of the IGF-binding domain on IGFBP-2. J Biol Chem. 2001 Jan 26; 276(4):2880-9.
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Variability of human hepatic UDP-glucuronosyltransferase activity. Acta Biochim Pol. 1999; 46(2):351-63.
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Synthesis of 5-azido-UDP-N-acetylhexosamine photoaffinity analogs and radiolabeled UDP-N-acetylhexosamines. Anal Biochem. 1998 May 01; 258(2):195-201.
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Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes. Biochemistry. 1998 Feb 03; 37(5):1274-82.
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Association of estramustine resistance in human prostatic carcinoma cells with modified patterns of tubulin expression. Biochem Pharmacol. 1998 Feb 01; 55(3):325-31.