Insulin-Like Growth Factor Binding Protein 2
"Insulin-Like Growth Factor Binding Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at the cellular level.
| Descriptor ID |
D018971
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| MeSH Number(s) |
D12.776.157.420.260
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 2".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 2" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 2" by people in Profiles.
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IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2. Proteins. 2022 09; 90(9):1732-1743.
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Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci. Circ Res. 2021 03 05; 128(5):e84-e101.
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Prominence of IL6, IGF, TLR, and Bioenergetics Pathway Perturbation in Lung Tissues of Scleroderma Patients With Pulmonary Fibrosis. Front Immunol. 2020; 11:383.
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Phases and Mechanisms of Embryonic Cardiomyocyte Proliferation and Ventricular Wall Morphogenesis. Pediatr Cardiol. 2019 Oct; 40(7):1359-1366.
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High-yield bacterial expression and structural characterization of recombinant human insulin-like growth factor binding protein-2. Arch Biochem Biophys. 2010 Sep 15; 501(2):195-200.
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Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures. Chem Commun (Camb). 2010 Jan 14; 46(2):216-8.
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Paradoxical effects of the phage display-derived peptide antagonist IGF-F1-1 on insulin-like growth factor-1 receptor signaling. Biochem Pharmacol. 2006 Jun 28; 72(1):53-61.
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Low insulin-like growth factor binding protein-2 expression is responsible for increased insulin receptor substrate-1 phosphorylation in mesangial cells from mice susceptible to glomerulosclerosis. Endocrinology. 2006 Jul; 147(7):3547-54.
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Insulin-like growth factor binding protein-2: contributions of the C-terminal domain to insulin-like growth factor-1 binding. Mol Pharmacol. 2006 Mar; 69(3):833-45.
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Synthesis and characterization of biotinylated forms of insulin-like growth factor-1: topographical evaluation of the IGF-1/IGFBP-2 AND IGFBP-3 interface. Biochemistry. 2004 Sep 14; 43(36):11533-45.