"Smad2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.
| Descriptor ID |
D051899
|
| MeSH Number(s) |
D12.644.360.024.334.500.200 D12.776.157.057.170.500.200 D12.776.476.024.428.500.200 D12.776.744.741.750 D12.776.930.806.500.200
|
| Concept/Terms |
Smad2 Protein- Smad2 Protein
- MAD-Related 2 Protein
- MAD Related 2 Protein
- MADR2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Smad2 Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- Smad Proteins [D12.644.360.024.334]
- Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
- Smad2 Protein [D12.644.360.024.334.500.200]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- Smad Proteins [D12.776.157.057.170]
- Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
- Smad2 Protein [D12.776.157.057.170.500.200]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- Smad Proteins [D12.776.476.024.428]
- Smad Proteins, Receptor-Regulated [D12.776.476.024.428.500]
- Smad2 Protein [D12.776.476.024.428.500.200]
- Phosphoproteins [D12.776.744]
- Smad Proteins, Receptor-Regulated [D12.776.744.741]
- Smad2 Protein [D12.776.744.741.750]
- Transcription Factors [D12.776.930]
- Smad Proteins [D12.776.930.806]
- Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
- Smad2 Protein [D12.776.930.806.500.200]
Below are MeSH descriptors whose meaning is more specific than "Smad2 Protein".
This graph shows the total number of publications written about "Smad2 Protein" by people in this website by year, and whether "Smad2 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 3 | 4 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Smad2 Protein" by people in Profiles.
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Effects of emodin, a plant-derived anthraquinone, on TGF-?1-induced cardiac fibroblast activation and function. J Cell Physiol. 2021 11; 236(11):7440-7449.
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Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies. Arterioscler Thromb Vasc Biol. 2019 10; 39(10):2067-2081.
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Simvastatin reduces TGF-?1-induced SMAD2/3-dependent human ventricular fibroblasts differentiation: Role of protein phosphatase activation. Int J Cardiol. 2018 Nov 01; 270:228-236.
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Glycoprotein A repetitions predominant (GARP) positively regulates transforming growth factor (TGF) ?3 and is essential for mouse palatogenesis. J Biol Chem. 2017 11 03; 292(44):18091-18097.
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Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-? Signaling in Murine Hepatic Stellate Cells. Am J Med Sci. 2018 02; 355(2):183-190.
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Lysocardiolipin acyltransferase regulates TGF-? mediated lung fibroblast differentiation. Free Radic Biol Med. 2017 11; 112:162-173.
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MicroRNA-29b inhibits TGF-?1-induced fibrosis via regulation of the TGF-?1/Smad pathway in primary human endometrial stromal cells. Mol Med Rep. 2016 May; 13(5):4229-37.
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Transforming Growth Factor-? Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion. Am J Pathol. 2016 05; 186(5):1351-60.
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M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo. Transl Res. 2016 Apr; 170:99-111.
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Lipoxin A4 Attenuates Constitutive and TGF-?1-Dependent Profibrotic Activity in Human Lung Myofibroblasts. J Immunol. 2015 Sep 15; 195(6):2852-60.