"Smad Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.
| Descriptor ID |
D051785
|
| MeSH Number(s) |
D12.644.360.024.334 D12.776.157.057.170 D12.776.260.713 D12.776.476.024.428 D12.776.930.806
|
| Concept/Terms |
Smad Proteins- Smad Proteins
- Mothers Against Decapentaplegic Homolog
- Sma- and Mad-Related Proteins
|
Below are MeSH descriptors whose meaning is more general than "Smad Proteins".
Below are MeSH descriptors whose meaning is more specific than "Smad Proteins".
This graph shows the total number of publications written about "Smad Proteins" by people in this website by year, and whether "Smad Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smad Proteins" by people in Profiles.
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Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Promoted Osteogenesis by Increasing Vesicle Trafficking, Wnt/Ca2+, and BMP/Smad Signaling. Int J Mol Sci. 2021 Nov 08; 22(21).
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MGMT-inhibitor in combination with TGF-?RI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells. Clin Transl Oncol. 2021 Mar; 23(3):612-619.
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MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15; 310(6):G347-58.
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MicroRNA-29b Inhibits Endometrial Fibrosis by Regulating the Sp1-TGF-?1/Smad-CTGF Axis in a Rat Model. Reprod Sci. 2016 Mar; 23(3):386-94.
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Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy. Thorax. 2015 Dec; 70(12):1138-48.
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Connective tissue disorders and cardiovascular complications: the indomitable role of transforming growth factor-beta signaling. Adv Exp Med Biol. 2014; 802:107-27.
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Hyperactive transforming growth factor-?1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. J Bone Miner Res. 2013 Dec; 28(12):2476-89.
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Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med. 2013 Nov 18; 210(12):2597-610.
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Breast cancer go sMAD: cyclin towards aggressive phenotypes. Cell Cycle. 2011 Jan 15; 10(2):187.
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The tale of transforming growth factor-beta (TGFbeta) signaling: a soign? enigma. IUBMB Life. 2009 Oct; 61(10):929-39.