Growth Hormone-Releasing Hormone
"Growth Hormone-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
| Descriptor ID |
D013007
|
| MeSH Number(s) |
D06.472.699.327.740.860 D12.644.400.400.740.860 D12.644.548.365.740.860 D12.776.631.650.405.740.860
|
| Concept/Terms |
Growth Hormone-Releasing Hormone- Growth Hormone-Releasing Hormone
- Growth Hormone Releasing Hormone
- GRF 1-44
- Growth Hormone-Releasing Factor 44
- Growth Hormone Releasing Factor 44
- Somatotropin-Releasing Factor 44
- Somatotropin Releasing Factor 44
- Somatotropin-Releasing Hormone
- Somatotropin Releasing Hormone
- Growth Hormone-Releasing Factor
- Growth Hormone Releasing Factor
- Somatocrinin
- Somatoliberin
- GHRH 1-44
|
Below are MeSH descriptors whose meaning is more general than "Growth Hormone-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Growth Hormone-Releasing Hormone".
This graph shows the total number of publications written about "Growth Hormone-Releasing Hormone" by people in this website by year, and whether "Growth Hormone-Releasing Hormone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Growth Hormone-Releasing Hormone" by people in Profiles.
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Inhibition of tumor growth by agonists of growth hormone-releasing hormone. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):11876-11878.
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Growth hormone-releasing hormone receptor splice variant 1 is frequently expressed in oral squamous cell carcinomas. Horm Cancer. 2012 Aug; 3(4):172-80.
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Growth hormone-releasing hormone: not only a neurohormone. Trends Endocrinol Metab. 2011 Aug; 22(8):311-7.
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Acceleration of wound healing by growth hormone-releasing hormone and its agonists. Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43):18611-5.
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Expression of growth hormone-releasing hormone receptor splice variant 1 in primary human melanomas. Regul Pept. 2008 Apr 10; 147(1-3):33-6.
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Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men. J Clin Endocrinol Metab. 2008 Mar; 93(3):944-50.
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Tripartite control of growth hormone secretion in women during controlled estradiol repletion. J Clin Endocrinol Metab. 2007 Jun; 92(6):2336-45.
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Expression of growth hormone-releasing hormone (GHRH) and splice variant of GHRH receptors in normal mouse tissues. Regul Pept. 2006 Sep 11; 136(1-3):105-8.
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Detection of growth hormone-releasing hormone in cytologic specimens of primary breast carcinoma. Acta Cytol. 2005 Jan-Feb; 49(1):108-9.
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Immunohistochemical detection of GHRH and its receptor splice variant 1 in primary human breast cancers. Eur J Endocrinol. 2004 Sep; 151(3):391-6.