Corticotropin-Releasing Hormone
"Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
| Descriptor ID |
D003346
|
| MeSH Number(s) |
D06.472.699.327.740.140 D12.644.400.400.740.140 D12.644.548.365.740.140 D12.776.631.650.405.740.140
|
| Concept/Terms |
Corticotropin-Releasing Hormone- Corticotropin-Releasing Hormone
- Corticotropin Releasing Hormone
- Corticoliberin
- Corticotropin-Releasing Factor
- Corticotropin Releasing Factor
- Corticotropin-Releasing Factor-41
- Corticotropin Releasing Factor 41
- CRF (ACTH)
- Corticotropin-Releasing Hormone-41
- Corticotropin Releasing Hormone 41
- CRF-41
- ACTH-Releasing Hormone
- ACTH Releasing Hormone
- ACTH-Releasing Factor
- ACTH Releasing Factor
|
Below are MeSH descriptors whose meaning is more general than "Corticotropin-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Corticotropin-Releasing Hormone" by people in this website by year, and whether "Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 1 | 3 |
| 2010 | 4 | 0 | 4 |
| 2011 | 2 | 1 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Corticotropin-Releasing Hormone" by people in Profiles.
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The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior in mice. Nat Commun. 2021 08 23; 12(1):5080.
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Opposing actions of CRF-R1 and CB1 receptors on VTA-GABAergic plasticity following chronic exposure to ethanol. Neuropsychopharmacology. 2018 09; 43(10):2064-2074.
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Essential Role of Ovarian Hormones in Susceptibility to the Consequences of Witnessing Social Defeat in Female Rats. Biol Psychiatry. 2018 09 01; 84(5):372-382.
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Impact of gender on corticotropin-releasing factor and noradrenergic sensitivity in cocaine use disorder. J Neurosci Res. 2017 01 02; 95(1-2):320-327.
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Extended Amygdala to Ventral Tegmental Area Corticotropin-Releasing Factor Circuit Controls Binge Ethanol Intake. Biol Psychiatry. 2017 06 01; 81(11):930-940.
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Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling. Psychoneuroendocrinology. 2016 May; 67:40-50.
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Activation of corticotropin releasing factor-containing neurons in the rat central amygdala and bed nucleus of the stria terminalis following exposure to two different anxiogenic stressors. Behav Brain Res. 2016 May 01; 304:92-101.
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NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking. Nat Neurosci. 2015 Apr; 18(4):545-52.
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CRF-R2 and the heterosynaptic regulation of VTA glutamate during reinstatement of cocaine seeking. J Neurosci. 2014 Jul 30; 34(31):10402-14.
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Alcohol dependence and free-choice drinking in mice. Alcohol. 2014 May; 48(3):287-93.