Sex Hormone-Binding Globulin
"Sex Hormone-Binding Globulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
| Descriptor ID |
D012738
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| MeSH Number(s) |
D12.776.124.790.223.800 D12.776.157.762 D12.776.377.715.182.800
|
| Concept/Terms |
Sex Hormone-Binding Globulin- Sex Hormone-Binding Globulin
- Globulin, Sex Hormone-Binding
- Hormone-Binding Globulin, Sex
- Sex Hormone Binding Globulin
- Testosterone-Estradiol Binding Globulin
- Binding Globulin, Testosterone-Estradiol
- Globulin, Testosterone-Estradiol Binding
- Testosterone Estradiol Binding Globulin
- Sex Steroid-Binding Protein
- Sex Steroid Binding Protein
- Steroid-Binding Protein, Sex
|
Below are MeSH descriptors whose meaning is more general than "Sex Hormone-Binding Globulin".
Below are MeSH descriptors whose meaning is more specific than "Sex Hormone-Binding Globulin".
This graph shows the total number of publications written about "Sex Hormone-Binding Globulin" by people in this website by year, and whether "Sex Hormone-Binding Globulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sex Hormone-Binding Globulin" by people in Profiles.
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Circulating sex hormone binding globulin levels are modified with intensive lifestyle intervention, but their changes did not independently predict diabetes risk in the Diabetes Prevention Program. BMJ Open Diabetes Res Care. 2020 12; 8(2).
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Higher Serum Sex Hormone-Binding Globulin Levels Are Associated With Incident Cardiovascular Disease in Men. J Clin Endocrinol Metab. 2019 12 01; 104(12):6301-6315.
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Cross-sectional and longitudinal determinants of serum sex hormone binding globulin (SHBG) in a cohort of community-dwelling men. PLoS One. 2018; 13(7):e0200078.
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Development and validation of a spontaneous preterm delivery predictor in asymptomatic women. Am J Obstet Gynecol. 2016 May; 214(5):633.e1-633.e24.
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A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma. Clin Cancer Res. 2015 Aug 01; 21(15):3420-7.
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Sex hormones and risk of breast cancer in premenopausal women: a collaborative reanalysis of individual participant data from seven prospective studies. Lancet Oncol. 2013 Sep; 14(10):1009-19.
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Estrogen elevates the peak overnight production rate of acylated ghrelin. J Clin Endocrinol Metab. 2008 Nov; 93(11):4440-7.
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Increased cortisol in the cerebrospinal fluid of women with functional hypothalamic amenorrhea. J Clin Endocrinol Metab. 2006 Apr; 91(4):1561-5.
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Greater secretion of growth hormone in black than in white men: possible factor in greater bone mineral density--a clinical research center study. J Clin Endocrinol Metab. 1995 Aug; 80(8):2291-7.
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A prospective study of endogenous hormones and breast cancer. Cancer Detect Prev. 1994; 18(2):79-85.