"4-Aminopyridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the POTASSIUM CHANNEL BLOCKERS with secondary effect on calcium currents which is used mainly as a research tool and to characterize channel subtypes.
| Descriptor ID |
D015761
|
| MeSH Number(s) |
D02.092.080.060 D03.383.725.050.060
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "4-Aminopyridine".
Below are MeSH descriptors whose meaning is more specific than "4-Aminopyridine".
This graph shows the total number of publications written about "4-Aminopyridine" by people in this website by year, and whether "4-Aminopyridine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Aminopyridine" by people in Profiles.
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Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin. Biochem Biophys Res Commun. 2022 10 01; 623:44-50.
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Editorial by concerned physicians: Unintended effect of the orphan drug act on the potential cost of 3,4-diaminopyridine. Muscle Nerve. 2016 Feb; 53(2):165-8.
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Neonatal rat cardiac fibroblasts express three types of voltage-gated K+ channels: regulation of a transient outward current by protein kinase C. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H1010-7.
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Presynaptic kappa-opioid and muscarinic receptors inhibit the calcium-dependent component of evoked glutamate release from striatal synaptosomes. J Neurochem. 1999 Sep; 73(3):1058-65.
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Opiate modulation of striatal dopamine and hippocampal norepinephrine release following morphine withdrawal. Neurochem Res. 1997 Mar; 22(3):239-48.