"Receptors, Neurokinin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.
Descriptor ID |
D018040
|
MeSH Number(s) |
D12.776.543.750.695.862.500 D12.776.543.750.720.600.830.500 D12.776.543.750.750.555.830.500
|
Concept/Terms |
Receptors, Neurokinin-1- Receptors, Neurokinin-1
- Receptors, Neurokinin 1
- Substance P Receptors
- Receptors, Substance P
- P Receptors, Substance
- NK-1 Receptor
- NK 1 Receptor
- Receptor, NK-1
- Receptors, NK-1
- Receptors, NK 1
- NK-1 Receptors
- NK 1 Receptors
- Tachykinin Receptor 1
- Neurokinin-1 Receptors
- Neurokinin 1 Receptors
- Receptors, SP-P
- Receptors, SP P
- SP-P Receptor
- Receptor, SP-P
- SP P Receptor
- SP-P Receptors
- SP P Receptors
- Substance-P Receptor
- Receptor, Substance-P
- Substance P Receptor
- P Receptor, Substance
- Receptor, Substance P
- Neurokinin-1 Receptor
- Neurokinin 1 Receptor
- Receptor, Neurokinin-1
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Neurokinin-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Tachykinin [D12.776.543.750.695.862]
- Receptors, Neurokinin-1 [D12.776.543.750.695.862.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Tachykinin [D12.776.543.750.720.600.830]
- Receptors, Neurokinin-1 [D12.776.543.750.720.600.830.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Tachykinin [D12.776.543.750.750.555.830]
- Receptors, Neurokinin-1 [D12.776.543.750.750.555.830.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Neurokinin-1".
This graph shows the total number of publications written about "Receptors, Neurokinin-1" by people in this website by year, and whether "Receptors, Neurokinin-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
---|
1995 | 1 | 0 | 1 |
2001 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Neurokinin-1" by people in Profiles.
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Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice. Am J Physiol Gastrointest Liver Physiol. 2011 Aug; 301(2):G297-305.
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Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome". J Biol Chem. 2006 Jul 14; 281(28):19346-57.
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Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J Neurosci. 2001 Sep 15; 21(18):7273-83.
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Use of beta-methylphenylalanine (beta MeF) residues to probe the nature of the interaction of substance P with its receptor: effects of beta MeF-containing substance P analogs on rabbit iris smooth muscle contraction. J Med Chem. 1995 Jun 23; 38(13):2478-82.