15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
"15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
| Descriptor ID |
D019796
|
| MeSH Number(s) |
D01.248.497.158.685.750.744.650.500.500 D01.339.431.374.744.650.500.500 D01.650.550.750.700.650.500.500 D02.389.338.638.650.500.500 D10.251.355.255.550.025.650.500.500 D23.469.050.175.725.025.650.500.500 D23.469.700.630.500
|
| Concept/Terms |
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
- 9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha
- 9,11-epoxymethano-PGH2
- 9,11 epoxymethano PGH2
- 11 alpha,9 alpha-Epoxymethano PGH2
- 11 alpha,9 alpha Epoxymethano PGH2
- (15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
- (15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid
- 9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha
U-44619- U-44619
- U 44619
- U46619
- U44619
- U-46619
- U 46619
|
Below are MeSH descriptors whose meaning is more general than "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid".
- Chemicals and Drugs [D]
- Inorganic Chemicals [D01]
- Electrolytes [D01.248]
- Ions [D01.248.497]
- Anions [D01.248.497.158]
- Oxides [D01.248.497.158.685]
- Peroxides [D01.248.497.158.685.750]
- Prostaglandin Endoperoxides [D01.248.497.158.685.750.744]
- Prostaglandins H [D01.248.497.158.685.750.744.650]
- Prostaglandin H2 [D01.248.497.158.685.750.744.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.248.497.158.685.750.744.650.500.500]
- Free Radicals [D01.339]
- Reactive Oxygen Species [D01.339.431]
- Peroxides [D01.339.431.374]
- Prostaglandin Endoperoxides [D01.339.431.374.744]
- Prostaglandins H [D01.339.431.374.744.650]
- Prostaglandin H2 [D01.339.431.374.744.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.339.431.374.744.650.500.500]
- Oxygen Compounds [D01.650]
- Oxides [D01.650.550]
- Peroxides [D01.650.550.750]
- Prostaglandin Endoperoxides [D01.650.550.750.700]
- Prostaglandins H [D01.650.550.750.700.650]
- Prostaglandin H2 [D01.650.550.750.700.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.650.550.750.700.650.500.500]
- Organic Chemicals [D02]
- Free Radicals [D02.389]
- Peroxides [D02.389.338]
- Prostaglandin Endoperoxides [D02.389.338.638]
- Prostaglandins H [D02.389.338.638.650]
- Prostaglandin H2 [D02.389.338.638.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D02.389.338.638.650.500.500]
- Lipids [D10]
- Fatty Acids [D10.251]
- Fatty Acids, Unsaturated [D10.251.355]
- Eicosanoids [D10.251.355.255]
- Prostaglandins [D10.251.355.255.550]
- Prostaglandin Endoperoxides [D10.251.355.255.550.025]
- Prostaglandins H [D10.251.355.255.550.025.650]
- Prostaglandin H2 [D10.251.355.255.550.025.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D10.251.355.255.550.025.650.500.500]
- Biological Factors [D23]
- Inflammation Mediators [D23.469]
- Autacoids [D23.469.050]
- Eicosanoids [D23.469.050.175]
- Prostaglandins [D23.469.050.175.725]
- Prostaglandin Endoperoxides [D23.469.050.175.725.025]
- Prostaglandins H [D23.469.050.175.725.025.650]
- Prostaglandin H2 [D23.469.050.175.725.025.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D23.469.050.175.725.025.650.500.500]
- Prostaglandins, Synthetic [D23.469.700]
- Prostaglandin Endoperoxides, Synthetic [D23.469.700.630]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D23.469.700.630.500]
Below are MeSH descriptors whose meaning is more specific than "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid".
This graph shows the total number of publications written about "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" by people in this website by year, and whether "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" by people in Profiles.
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Regulation of the tumor suppressor FOXO3 by the thromboxane-A2 receptors in urothelial cancer. PLoS One. 2014; 9(9):e107530.
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Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen. Pediatr Res. 2007 Sep; 62(3):313-8.
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Progesterone regulation of vascular thromboxane A(2) receptors in rhesus monkeys. Am J Physiol Heart Circ Physiol. 2001 Oct; 281(4):H1498-507.
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Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):4888-93.
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Preoperative thromboxane A2/prostaglandin H2 receptor activity predicts early graft thrombosis. J Vasc Surg. 1998 Feb; 27(2):317-25; discussion 326-8.
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Modification on ligand binding to TXA2/PGH2 receptors by diethylpyrocarbonate. Adv Exp Med Biol. 1997; 400A:235-40.
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Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase. Am J Physiol. 1996 Jan; 270(1 Pt 2):F31-8.
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Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets. J Pharmacol Exp Ther. 1994 Sep; 270(3):1192-6.
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Agonist-induced phosphorylation of human platelet TXA2/PGH2 receptors. Biochim Biophys Acta. 1994 Mar 10; 1221(1):83-8.
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Testosterone treatment enhances thromboxane A2 mimetic induced coronary artery vasoconstriction in guinea pigs. Eur J Clin Invest. 1994 Feb; 24 Suppl 1:50-2.