"Medulloblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
Descriptor ID |
D008527
|
MeSH Number(s) |
C04.557.465.625.600.380.515 C04.557.465.625.600.590.500 C04.557.470.670.380.515 C04.557.470.670.590.500 C04.557.580.625.600.380.515 C04.557.580.625.600.590.500
|
Concept/Terms |
Melanocytic Medulloblastoma- Melanocytic Medulloblastoma
- Medulloblastoma, Melanocytic
- Medulloblastomas, Melanocytic
- Melanocytic Medulloblastomas
Medulloblastoma, Childhood- Medulloblastoma, Childhood
- Childhood Medulloblastoma
- Childhood Medulloblastomas
- Medulloblastomas, Childhood
Arachnoidal Cerebellar Sarcoma, Circumscribed- Arachnoidal Cerebellar Sarcoma, Circumscribed
- Sarcoma, Cerebellar, Circumscribed Arachnoidal
- Medulloblastoma, Desmoplastic
- Desmoplastic Medulloblastoma
- Desmoplastic Medulloblastomas
- Medulloblastomas, Desmoplastic
Medulloblastoma, Adult- Medulloblastoma, Adult
- Adult Medulloblastoma
- Adult Medulloblastomas
- Medulloblastomas, Adult
|
Below are MeSH descriptors whose meaning is more general than "Medulloblastoma".
Below are MeSH descriptors whose meaning is more specific than "Medulloblastoma".
This graph shows the total number of publications written about "Medulloblastoma" by people in this website by year, and whether "Medulloblastoma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2003 | 1 | 2 | 3 |
2004 | 1 | 0 | 1 |
2005 | 2 | 0 | 2 |
2006 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2015 | 3 | 0 | 3 |
2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2022 | 3 | 0 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Medulloblastoma" by people in Profiles.
-
A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog-Dependent Tumor Growth. Mol Cancer Res. 2022 Nov 03; 20(11):1598-1610.
-
A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma. Clin Cancer Res. 2022 09 15; 28(18):3950-3957.
-
Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse. Sci Adv. 2022 07 22; 8(29):eabj9138.
-
A CK1a Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma. Clin Cancer Res. 2019 02 15; 25(4):1379-1388.
-
Immunological low-dose radiation modulates the pediatric medulloblastoma antigens and enhances antibody-dependent cellular cytotoxicity. Childs Nerv Syst. 2017 Mar; 33(3):429-436.
-
Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma. Neuro Oncol. 2016 06; 18(6):881-7.
-
Clinical Outcomes Among Children With Standard-Risk Medulloblastoma Treated With Proton and Photon Radiation Therapy: A Comparison of Disease Control and Overall Survival. Int J Radiat Oncol Biol Phys. 2016 Jan 01; 94(1):133-138.
-
A Phase 1 Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients with Refractory or Recurrent Neuroblastoma or Medulloblastoma. Pediatr Blood Cancer. 2016 Jan; 63(1):39-46.
-
The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. J Biol Chem. 2014 Dec 19; 289(51):35494-502.
-
Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Res. 2014 Sep 01; 74(17):4811-21.