Phosphopyruvate Hydratase
"Phosphopyruvate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.
| Descriptor ID |
D010751
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| MeSH Number(s) |
D08.811.520.241.300.500
|
| Concept/Terms |
Phosphopyruvate Hydratase- Phosphopyruvate Hydratase
- Hydratase, Phosphopyruvate
- 2-Phospho-D-Glycerate Hydrolase
- 2 Phospho D Glycerate Hydrolase
- Enolase
- 2-Phospho-D-Glycerate Hydro-Lyase
- 2 Phospho D Glycerate Hydro Lyase
- Hydro-Lyase, 2-Phospho-D-Glycerate
- 2-Phosphoglycerate Dehydratase
- 2 Phosphoglycerate Dehydratase
- Dehydratase, 2-Phosphoglycerate
gamma-Enolase- gamma-Enolase
- gamma Enolase
- Nervous System-Specific Enolase
- Enolase, Nervous System-Specific
- Nervous System Specific Enolase
- System-Specific Enolase, Nervous
- Neuron-Specific Enolase
- Enolase, Neuron-Specific
- Neuron Specific Enolase
- Enolase 2
alpha-Enolase- alpha-Enolase
- alpha Enolase
- Non-Neuronal Enolase
- Enolase, Non-Neuronal
- Non Neuronal Enolase
beta-Enolase- beta-Enolase
- beta Enolase
- Muscle-Specific Enolase
- Enolase, Muscle-Specific
- Muscle Specific Enolase
- Enolase 3
|
Below are MeSH descriptors whose meaning is more general than "Phosphopyruvate Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Phosphopyruvate Hydratase".
This graph shows the total number of publications written about "Phosphopyruvate Hydratase" by people in this website by year, and whether "Phosphopyruvate Hydratase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 1 | 2 | 3 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 5 | 5 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphopyruvate Hydratase" by people in Profiles.
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E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects. JCI Insight. 2021 12 22; 6(24).
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Enolase inhibition alters metabolic hormones and inflammatory factors to promote neuroprotection in spinal cord injury. Neurochem Int. 2020 10; 139:104788.
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Targeting Enolase in Reducing Secondary Damage in Acute Spinal Cord Injury in Rats. Neurochem Res. 2017 Oct; 42(10):2777-2787.
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Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice. Neurobiol Dis. 2016 Dec; 96:248-260.
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Neuron specific enolase: a promising therapeutic target in acute spinal cord injury. Metab Brain Dis. 2016 06; 31(3):487-95.
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Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats. Exp Neurol. 2015 May; 267:135-142.
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Disruption of HLA class II antigen presentation in Burkitt lymphoma: implication of a 47,000 MW acid labile protein in CD4+ T-cell recognition. Immunology. 2014 Jul; 142(3):492-505.
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Glomerular autoimmune multicomponents of human lupus nephritis in vivo: a-enolase and annexin AI. J Am Soc Nephrol. 2014 Nov; 25(11):2483-98.
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The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nat Neurosci. 2013 Jan; 16(1):55-63.
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Proteomic analysis of mice expressing human ApoE demonstrates no differences in global protein solubility between APOE 3 and APOE 4 young mice. Electrophoresis. 2012 Dec; 33(24):3745-55.